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| Urbano,L; Portilla,E.C; Builes,J.J; Gusmão,L; Sierra-Torres,C.H. |
| Genetic markers with allele distribution differences in human populations provide human ancestry information that can be used to evaluate admixture proportions in different ethnic groups, including stratification in genetic association studies. The aim of this study was to determine the African, European and Native American admixture proportion by making use of 46 insertion-deletion informative ancestry record markers set in 500 Latin American people in the Department of Cauca, Colombia. Allelic frequencies were established, Hardy Weinberg test was performed, comparisons in genetic distances among population groups were estimated using Arlequin v 3.5, and STRUCTURE v 2.3.4 software was used to determine the population’s ancestry admixture. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Genetic ancestry; InDels; AIMs; Latin America; Human populations. |
| Ano: 2016 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332016000300004 |
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| García,Angelina; Dermarchi,Darío A.; Tovo-Rodrigues,Luciana; Pauro,Maia; Callegari-Jacques,Sidia M.; Salzano,Francisco M.; Hutz,Mara H.. |
| The population of Argentina has already been studied with regard to several genetic markers, but much more data are needed for the appropriate definition of its genetic profile. This study aimed at investigating the admixture patterns and genetic structure in Central Argentina, using biparental markers and comparing the results with those previously obtained by us with mitochondrial DNA (mtDNA) in the same samples. A total of 521 healthy unrelated individuals living in 13 villages of the Córdoba and San Luis provinces were tested. The individuals were genotyped for ten autosomal ancestry informative markers (AIMs). Allele frequencies were compared with those of African, European and Native American populations, chosen to represent parental contributions.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: AIMs; Córdoba; San Luis; Migration; Population structure. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000300324 |
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